Mateus Domingues de Barros¹; Rebeca Xavier da Cunha¹; João Ricardhis
Saturnino de Oliveira¹; Ana Paula Sant’Anna da Silva¹; Layza Fernanda Gomes
Bezerra¹; Vera Lúcia de Menezes Lima¹
¹Laboratório de Lipídios e Aplicações de Biomoléculas em Doenças Prevalentes e Negligenciadas.
Departamento de Bioquímica, Centro de Biociências, Universidade Federal de Pernambuco, Avenida Professor Moraes Rego, 1235, CEP 50670-901 Recife, PE, Brasil.
¹Laboratory of Lipids and Applications of Biomolecules in Prevalent and Neglected Diseases. Department of Biochemistry, Center for Biosciences, Federal University of Pernambuco, Avenida Professor Moraes Rego, 1235, Zip Code 50670-901 Recife, PE, Brazil
Corresponding Author: Mateus Domingues de Barros, E-mail: mateusdb1@gmail.com
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https://doi.org/10.63711/ijdr.net20250308
ABSTRACT
In view of the healing process, factors such as depth, length and microorganisms infection can delay cicatrization, requiring the search for therapeutic alternatives, such as plant-derived metabolites. Tannins are secondary metabolites constituents of plants whose action on wounds is the most reported. The present work aims to do an exploratory descriptive literature review of tannins action as a therapeutic agent in wound healing through different mechanisms. Tannins work by forming a film on the lesion, creating an environment favorable to cell anticipation and extracellular matrix agents such as collagen and elastin, also having antioxidant and anti-inflammatory action. This polyphenol can adapt to different conditions according to their specificity and degree of aggression, thus proving to be superior to conventional means that have already been eliminated, leading to a brief discussion about these mechanisms that act synergistically during the healing process assisting in the development of new therapies.
Keywords: Natural products, Healing, Polyphenols, Secondary metabolites
